Knee Injections

For patient comfort and to assist in deciding upon therapeutic efficacy, the Advanced Pain Institute offers steroid injection, PRP and minimally-invasive arthroscopy for the knee.

Steroid Injection

A knee injection is a shot of medicine into the knee joint. The medicine helps relieve pain and inflammation. It can also help diagnose the source of knee pain.


For this procedure, a health care provider inserts a needle in the knee and injects medicine into the joint. The provider uses a real-time x-ray (fluoroscopy) to see where to place the needle in the joint. You may be given medicine to help you relax.

For the procedure:

  • You will lie on the x-ray table, and your knee area will be cleaned.
  • A numbing medicine will be applied to the injection site.
  • A small needle will be guided into the joint area while the provider watches the placement on the screen.
  • Once the needle is in the right spot, a small amount of contrast dye is injected so the provider can see where to place the medicine.
  • The steroid medicine is slowly injected into the joint.

After the injection, you will remain on the table for another 5 to 10 minutes or so. Your provider will then ask you to move the knee to see if it is still painful. It may be a few days before you notice any pain relief.

PRP & Stem Cell Therapy

What is Platelet Rich Plasma Therapy?

Blood plasma is the liquid component of blood that makes up about half of its total volume. Blood plasma that is rich in small cell fragments called platelets can be used to treat a number of musculoskeletal conditions. Platelets circulate in the blood of all mammals, and contain many growth factors that are known to stimulate the growth and healing of both bones and soft tissues. Osteoarthritis is one of the major conditions treated by platelet-rich plasma therapy. Osteoarthritis is a form of arthritis that involves the breakdown of cartilage in the joints. Platelet-rich plasma can also be used to heal tendon and ligament problems that result in hip pain, knee pain, shoulder pain, and elbow pain. Many of these problems stem from the wear and tear caused by the repetitive motions involved in certain sports, and athletes are increasingly using platelet-rich plasma therapy to treat tennis elbow and other sports injuries.

How Does Platelet Rich Plasma Therapy Work?

  • The body’s first response to soft tissue injury is to deliver platelet cells
  • Packed with growth and healing factors, platelets initiate repair and attract the critical assistance of stem cells
  • PRP’s natural healing process intensifies the body’s efforts by delivering a higher concentration of platelets directly into the area in need
  • To create PRP, a small sample of your blood is drawn (similar to a lab test sample) and placed in a centrifuge that spins the blood at high speeds, separating the platelets from the other components. The process is handled manually by a lab technician, producing higher concentrations of platelets and a much more pure concentration of the beneficial blood components
  • The PRP is then injected directly into the injured area of bone or soft tissue to facilitate the healing process

Benefits of Platelet-Rich Plasma Therapy

Compared to cortisone injections and other methods of treating osteoarthritis and tendon injuries, platelet-rich plasma therapy has a low risk of complications. Because the injections actually heal the affected areas, the relief from osteoarthritis pain can last for an extended period of time. The treatment can also provide long-term relief from hip pain, knee pain, elbow pain, foot pain, and other pain caused by inflamed connective tissue. Improvements in these conditions are typically noticeable after a few weeks, and the pain relief gradually increases as the tissue is repaired. Since the plasma is drawn from the patient’s own body, there is almost no risk of rejection from this procedure.

Details of the Procedure

Platelet-rich plasma therapy takes about 90 minutes from start to finish. Platelet-rich plasma is obtained by drawing blood from the patient and placing it in a centrifuge for about 15 minutes. The centrifuge spins at a high speed, separating the PRP from the rest of the patient’s blood particles. Once the layer of platelet rich plasma is isolate, it is injected directly into the injured area of bone or soft tissue to facilitate the healing process. The body responds by increasing its natural healing processes in the area. Some procedures consist of a single injection while others involve multiple treatments over an extended period of time.

Potential Risks

The side effects of the procedure are relatively rare. They include a very low risk of infection when a needle is inserted into the skin. The injection site may also bleed or bruise after the procedure. Patients who suffer from bleeding disorders or who take a “blood thinners” that inhibits blood clotting should avoid platelet-rich plasma therapy, if these blood thinners cannot be held prior to the injection. While any knee, elbow, or shoulder pain should eventually subside, some patients experience increased inflammation and pain after the injection.

Recovery Time

Patients are typically instructed to avoid strenuous activity for a few days, although most can return to their jobs the next day. A physical therapy routine will most likely be prescribed by your physician to reduce pain and increase mobility.

What is Stem Cell Therapy?

Stem Cells are undifferentiated cells that have ability to replace dying cells and regenerate damaged tissue. A high concentration of these cells are obtain from the patient’s own bone marrow or fat tissues (adipose) or from a purified amniotic tissue. Our practice uses a sterile closed surgical process to obtain the stem cells. Once obtained, the cells are isolated with a specialized centrifuge and then injected into the painful area on the same day using special imaging to make sure the cells are placed exactly where they are needed.

How Does Stem Cell Therapy Work?

Adult stem cells usually remain dormant unless they detect some kind of tissue injury. Then the ‘undifferentiated’ stem cells are called to areas of injury where they are capable of regenerating healthy cells. Sometimes our body’s own healing response is not enough. That’s when a concentrated source of stem cells is needed. Stem Cell therapy obtains high concentrations of cells to create an environment for the body to heal itself without the need for medications or steroid injections. When stem cells are injected into an area of injury, they enable the body’s natural healing processes to be dramatically accelerated. The cells can stimulate the formation of many different types of tissue including cartilage, tendon, ligaments, bone and fibrous connective tissues.

Minimally-Invasive Arthroscopy

What Is Knee Arthroscopy?

Knee arthroscopy is a surgical technique that can diagnose and treat problems in the knee joint. During the procedure, your surgeon will make a very small incision and insert a tiny camera — called an arthroscope — into your knee. This allows them to view the inside of the joint on a screen. The surgeon can then investigate a problem with the knee and, if necessary, correct the issue using small instruments within the arthroscope.

Arthroscopy diagnoses several knee problems, such as a torn meniscus or a misaligned patella (kneecap). It can also repair the ligaments of the joint. There are limited risks to the procedure and the outlook is good for most patients. Your recovery time and prognosis will depend on the severity of the knee problem and the complexity of the required procedure.

Why Do I Need Knee Arthroscopy?

Your doctor may recommend that you undergo a knee arthroscopy if you’re experiencing knee pain. Your doctor might have already diagnosed the condition causing your pain, or they may order the arthroscopy to help find a diagnosis. In either case, an arthroscopy is a useful way for doctors to confirm the source of knee pain and treat the problem.

Arthroscopic surgery can diagnose and treat knee injuries, including:

  • Torn anterior or posterior cruciate ligaments
  • Torn meniscus (the cartilage between the bones in the knee)
  • Patella that’s out of position
  • Pieces of torn cartilage that are loose in the joint
  • Removal of a Baker’s cyst
  • Fractures in the knee bones
  • Swollen synovium (the lining in the joint)






Advanced Pain Institute

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Arcadia: (626) 445-2371
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638 W Duarte Rd Suite 18,
Arcadia, CA 91007

16250 Ventura Blvd #165,
Encino, CA 91436